abstract：BACKGROUND:Ucche (Momordica charantia L. var. muricata (Willd.) Chakravarty) has been reported to possess many benefits and medicinal properties. However, the protective effect of ucche against carbon tetrachloride (CCl4) induced hepatotoxicity have not been clarified fully yet. The aim of the present study was to inve...

journal_title：BMC complementary and alternative medicine

authors： Sagor AT,Chowdhury MR,Tabassum N,Hossain H,Rahman MM,Alam MA

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:The use of complementary and alternative medicine (CAM) persists, despite the availability of conventional medicine (CM), modernisation, globalisation, technological advancement, and limited scientific evidence supporting CAM. People with cardiovascular diseases often use CAM, despite possible major adverse ...

journal_title：BMC complementary and alternative medicine

authors： Bahall M

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:The fruit of Cyrtocarpa procera is used to treat stomach diseases by people living in San Rafael, Coxcatlan, Puebla. This work investigated the antibacterial, antioxidant, cytotoxic and anti-inflammatory activities of the fruit produced by this species. METHODS:Methanol extract was obtained by maceration. A...

journal_title：BMC complementary and alternative medicine

authors： Martinez-Elizalde KS,Jimenez-Estrada M,Flores CM,Hernandez LB,Rosas-Lopez R,Duran-Diaz A,Nieto-Yañez OJ,Barbosa E,Rodriguez-Monroy MA,Canales-Martinez M

更新日期：2015-03-21 00:00:00

abstract：BACKGROUND:Short-term vasodilatation in the pain area after dry needling (DN) of active trigger points (TrPs) was recorded in several cases of sciatica. Moreover, the presence of TrPs in sciatica patients secondary to primary lesion was suggested. Still, it is not known how often they occur and if every TrPs can provok...

journal_title：BMC complementary and alternative medicine

authors： Skorupska E,Rychlik M,Samborski W

更新日期：2015-03-20 00:00:00

abstract：BACKGROUND:Our preliminary studies indicated that electroacupuncture (EA) at the ST36 and Ashi acupoints could promote regeneration of the rabbit gastrocnemius (GM) by improving microcirculation perfusion, promoting the recovery of myofiber structures, and inhibiting excessive fibrosis. However, the effects of EA on re...

journal_title：BMC complementary and alternative medicine

authors： Liu S,Wang R,Luo D,Xu Q,Xiao C,Lin P,Yu Z,Zhao X,Cai R,Ma J,Zhang Q,Wang Y

更新日期：2015-03-19 00:00:00

abstract：BACKGROUND:Breast cancer-related mortality increases annually. The efficacy of current breast cancer treatments is limited, and they have numerous side effects and permit high recurrence. Patients with estrogen receptor (ER)-negative or triple-negative breast cancer are particularly difficult to treat. Treatment for th...

journal_title：BMC complementary and alternative medicine

authors： Hsu RJ,Hsu YC,Chen SP,Fu CL,Yu JC,Chang FW,Chen YH,Liu JM,Ho JY,Yu CP

更新日期：2015-03-14 00:00:00

abstract：BACKGROUND:Samsoeum has long been used in Korea and other Asian countries as a traditional medicine to treat various diseases. In the present study, we investigated the antiasthma effect of the herbal medicine Samsoeum water extract (SSEW) using an in vivo ovalbumin (OVA)-induced asthmatic model. METHODS:Female BALB/c...

journal_title：BMC complementary and alternative medicine

authors： Jeon WY,Shin IS,Shin HK,Lee MY

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:The use of herbal medicines as complements or alternatives to orthodox medicines has been on the increase. There has been the erroneous belief that these medicines are free from adverse effects. Schefflera barteri is popularly used in the West region of Cameroon for the treatment of various diseases such as ...

journal_title：BMC complementary and alternative medicine

authors： Atsafack SS,Kuiate JR,Mouokeu RS,Koanga Mogtomo ML,Tchinda AT,De Dieu TJ,Magnifouet Nana H,Ebelle Etame RM,Biyiti L,Ngono Ngane RA

更新日期：2015-03-07 00:00:00

abstract：BACKGROUND:Inverse docking technology has been a trend of drug discovery, and bioinformatics approaches have been used to predict target proteins, biological activities, signal pathways and molecular regulating networks affected by drugs for further pharmacodynamic and mechanism studies. METHODS:In the present paper, ...

journal_title：BMC complementary and alternative medicine

authors： Yin L,Zheng L,Xu L,Dong D,Han X,Qi Y,Zhao Y,Xu Y,Peng J

更新日期：2015-03-05 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is an epidemic and progressive health problem which is mainly a consequence of cigarette smoking, and associated with lung inflammation. Anti-inflammatory property of Zataria multiflora (Z. multiflora) and its constituent, carvacrol was shown in various inflammato...

journal_title：BMC complementary and alternative medicine

authors： Boskabady MH,Gholami Mahtaj L

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Although Ojeok-san (OJS), an oriental herbal formula, has been used in Asian countries including Korea, China and Japan to treat the common cold and illnesses including fatigue and gastrointestinal disorders, there is little information of its safety and toxicity in vivo and in vitro. METHODS:In the present...

journal_title：BMC complementary and alternative medicine

authors： Jeong SJ,Huh JI,Shin HK

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:In our previous studies, it was evident that the dichloromethane-methanol (1:1 v/v) stem barks extract of Polyscias fulva and fractions (ethyl acetate, n-butanol and residue) demonstrated interesting antidermatophytic activities. So, as a continuity of that, this work aimed at identifying active principles w...

journal_title：BMC complementary and alternative medicine

authors： Njateng GS,Du Z,Gatsing D,Nanfack Donfack AR,Feussi Talla M,Kamdem Wabo H,Tane P,Mouokeu RS,Luo X,Kuiate JR

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:The anti-inflammatory activity of Andrographis paniculata (Acanthaceae), a traditional medicine widely used in Asia, is commonly attributed to andrographolide, its main secondary metabolite. Commercial A. paniculata extracts are standardised to andrographolide content. We undertook the present study to inves...

journal_title：BMC complementary and alternative medicine

authors： Low M,Khoo CS,Münch G,Govindaraghavan S,Sucher NJ

更新日期：2015-02-07 00:00:00

abstract：BACKGROUND:Annona muricata (A. muricata) is widely distributed in Asia, Africa and South America. Different parts of this plant are used to treat several diseases in Cameroon. The aim of this study is to determine the in vitro anti-proliferative effects and apoptotic events of A. muricata extracts on HL-60 cells as wel...

journal_title：BMC complementary and alternative medicine

authors： Pieme CA,Kumar SG,Dongmo MS,Moukette BM,Boyoum FF,Ngogang JY,Saxena AK

更新日期：2014-12-24 00:00:00

abstract：BACKGROUND:Carrageenan is a linear sulphated polysaccharide extracted from red seaweed of the Rhodophyceae family. It has broad spectrum of applications in biomedical and biopharmaceutical field. In this study, we determined the cytotoxicity of degraded and undegraded carrageenan in human intestine (Caco-2; cancer and ...

journal_title：BMC complementary and alternative medicine

authors： Ariffin SH,Yeen WW,Abidin IZ,Abdul Wahab RM,Ariffin ZZ,Senafi S

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Acetaminophen (APAP)-induced toxicity is a predominant cause of acute hepatic and renal failure. In both humans and rodents toxicity begins with a reactive metabolite that binds to proteins. This leads to mitochondrial dysfunction and nuclear DNA fragmentation resulting in necrotic cell death. Pleurotus ostr...

journal_title：BMC complementary and alternative medicine

authors： Naguib YM,Azmy RM,Samaka RM,Salem MF

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Paclitaxel induced fatigue still remains underrecognized and undertreated, partly because of limited understanding of its pathophysiology and lack of effective treatments. This study is aim to evaluate the anti-fatigue effects and mechanism of Bu-Zhong-Yi-Qi pill in murine 4 T1 breast cancer mice were treate...

journal_title：BMC complementary and alternative medicine

authors： Ouyang M,Liu Y,Tan W,Xiao Y,Yu K,Sun X,Huang Y,Cheng J,Luo R,Zhao X

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Pain and anxiety occurring from cardiovascular disease are associated with long-term health risks. Integrative medicine (IM) therapies reduce pain and anxiety in small samples of hospitalized cardiovascular patients within randomized controlled trials; however, practice-based effectiveness research has been ...

journal_title：BMC complementary and alternative medicine

authors： Johnson JR,Crespin DJ,Griffin KH,Finch MD,Rivard RL,Baechler CJ,Dusek JA

更新日期：2014-12-13 00:00:00

abstract：BACKGROUND:Huachansu injection (HCS) is a water-soluble preparation made from Bufo gargarizans's skin, which has been widely used in clinics for tumor therapy in China. Though the anti-cancer activity of HCS has been verified through studies in vitro and in vivo, there is little research about its potential anti-metast...

journal_title：BMC complementary and alternative medicine

authors： Yin JH,Zhu XY,Shi WD,Liu LM

更新日期：2014-12-13 00:00:00

abstract：BACKGROUND:Isoflavones are naturally occurring plant chemicals belonging to the "phytoestrogen" class. The aim of the present study was to examine the effects of isoflavones obtained from Cordyceps sinensis (CSIF) on development of estrogen deficiency-induced osteoporosis in ovariectomized rats. METHODS:After the rats...

journal_title：BMC complementary and alternative medicine

authors： Zhang DW,Wang ZL,Qi W,Zhao GY

更新日期：2014-12-13 00:00:00

abstract：BACKGROUND:The young shoots of Rubus idaeus are traditionally used as a herbal remedy in common cold, fever and flu-like infections yet there is no research concerning this plant material. The aim of the study was to evaluate the chemical composition and biological properties of raspberry shoots from 11 cultivar variet...

journal_title：BMC complementary and alternative medicine

authors： Krauze-Baranowska M,Głód D,Kula M,Majdan M,Hałasa R,Matkowski A,Kozłowska W,Kawiak A

更新日期：2014-12-12 00:00:00

abstract：BACKGROUND:The safety of Deltamethrin (DM) has been raised as a point of concern. The current investigation was envisaged to explore the responsiveness of oxidative stress parameters, DNA fragmentation and expression levels of TP53, cycloxygenase 2 (COX2) and cytochrome p4502E1 (CYP2E1) as toxicological endpoint in rat...

journal_title：BMC complementary and alternative medicine

authors： Galal MK,Khalaf AA,Ogaly HA,Ibrahim MA

更新日期：2014-12-02 00:00:00

abstract：BACKGROUND:Alternanthera sessilis is a popular vegetable and used in traditional medicinal practice of Bangladesh and other parts of Asia to relive tiredness, laziness, and sleeps as well as pain and inflammation. However, no report was found on the neuropharmacological and analgesic activity of this plant to-date. Pre...

journal_title：BMC complementary and alternative medicine

authors： Mondal H,Saha S,Awang K,Hossain H,Ablat A,Islam MK,Jahan IA,Sadhu SK,Hossain MG,Shilpi JA,Uddin SJ

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:Yukyung karne (YK) is a traditional Tibetan formulation used for many centuries for the treatment of ovarian cancer. However, the pharmacological basis of its anticancer property is not well understood. In the present study, the anticancer property of YK was investigated in cell culture. METHODS:The growth ...

journal_title：BMC complementary and alternative medicine

authors： Choedon T,Dolma D,Mathan G,Kumar V

更新日期：2014-10-07 00:00:00

abstract：BACKGROUND:Mitochondrial dysfunction has been implicated in neuronal apoptosis associated with neurodegenerative diseases such as Huntington's disease (HD). Animals that are administered 3-nitropropionic acid (3-NP), a mitochondrial toxin that specifically inhibits complex II of the mitochondrial electron transport cha...

journal_title：BMC complementary and alternative medicine

authors： Im AR,Chae SW,Zhang GJ,Lee MY

更新日期：2014-10-03 00:00:00

abstract：BACKGROUND:Idiopathic infertility is a significant number of causes of male infertility. Empirical treatments are used for idiopathic male infertility, and antioxidant supplementation is a kind of management of oxidative stress related infertility. We investigated the antioxidant effects of the modified Ojayeonjonghwan...

journal_title：BMC complementary and alternative medicine

authors： Bae WJ,Ha US,Kim KS,Kim SJ,Cho HJ,Hong SH,Lee JY,Wang Z,Hwang SY,Kim SW

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Insampaedok-san (ren-shen-bai-du-san in Chinese) is a traditional herbal formula widely used for the treatment of respiratory diseases in Korea and China. In this study, we investigated the acute oral toxicity of an Insampaedok-san water extract (ISSE) in rats and the antiasthmatic effects of ISSE and its me...

journal_title：BMC complementary and alternative medicine

authors： Kim Y,Lee MY,Kim OS,Jeon WY,Shin HK

更新日期：2014-09-29 00:00:00

abstract：BACKGROUND:The Consolidated Standards for Reporting Trials (CONSORT) are aimed to standardize clinical trial reporting. Our objective is to compare the quality of randomized clinical trials (RCTs) of traditional Chinese medicine (TCM) published in 2005-2009 and 2011-2012 according to the current CONSORT statements and ...

journal_title：BMC complementary and alternative medicine

authors： Li J,Liu Z,Chen R,Hu D,Li W,Li X,Chen X,Huang B,Liao L

更新日期：2014-09-26 00:00:00

abstract：BACKGROUND:Rhizoma Menispermi (RM) is the dried root of Menispermum dauricum DC, which is traditionally used to treat swelling and pain for sore throat, enteritis and rheumatic arthralgia in the clinic, but its bioactive compounds remain unclear. METHODS:In this study, RM extract was administered orally to ICR mice fo...

journal_title：BMC complementary and alternative medicine

authors： Sun D,Zhou M,Ying X,Cheng B,Han Y,Nie Y,Hou Y,Bai G

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Danggui (Radix Angelicae Sinensis) is an herb often used in Traditional Chinese medicine. It is used to promote blood flow and has been used in the treatment of myocardial ischemia-reperfusion injury in animal models. Angiotensin II (Ang II) has been shown to play important roles in mediating cardiovascular ...

journal_title：BMC complementary and alternative medicine

authors： Huang CY,Kuo WW,Kuo CH,Tsai FJ,Liu PY,Hsieh DJ

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Acupuncture is an effective complement to pharmacological therapy in the alleviation of chronic pelvic inflammatory disease (PID). It has mild or no side effects; however, a minimum of 3 months of therapy is required to guarantee a beneficial outcome. This study investigates why patients insist on acupunctur...

journal_title：BMC complementary and alternative medicine

authors： Liang Y,Gong D

更新日期：2014-09-21 00:00:00

abstract：BACKGROUND:The search for natural products as potential cytotoxic agents has yielded promising candidates. However multidrug resistance (MDR) is still a major hurdle for patients receiving chemotherapy. In the present study, we evaluated the cytotoxicity of the methanol extracts of four dietary Aframomum plant species ...

journal_title：BMC complementary and alternative medicine

authors： Kuete V,Ango PY,Yeboah SO,Mbaveng AT,Mapitse R,Kapche GD,Ngadjui BT,Efferth T

更新日期：2014-09-19 00:00:00

abstract：BACKGROUND:Emergence of drug-resistant strains of Candida and inefficiency of conventional antifungal therapy has necessitated the search for alternative and new antifungal agents. Inhibition of virulence and biofilm are the potential drug targets. In this study, the oils of Carum copticum, Thymus vulgaris and their ma...

journal_title：BMC complementary and alternative medicine

authors： Khan MS,Ahmad I,Cameotra SS,Botha F

更新日期：2014-09-15 00:00:00

abstract：BACKGROUND:Obesity is an important risk factor for cardiovascular and metabolic diseases and could affect mortality rates. Body mass index (BMI) and waist circumference (WC) have been used to classify obesity, and waist-to-hip ratio (WHR) has recently emerged as a discriminator of cardiovascular disease. Sasang constit...

journal_title：BMC complementary and alternative medicine

authors： Baek Y,Park K,Lee S,Jang E

更新日期：2014-08-13 00:00:00

abstract：BACKGROUND:We hypothesized that C. borivilianum root, known to improve male reproductive performance, prevents impairment in characteristics, morphology and elevation of oxidative stress in sperm of diabetics. We therefore investigated the effect of aqueous root extract of C. borivilianum on these parameters in diabeti...

journal_title：BMC complementary and alternative medicine

authors： Giribabu N,Kumar KE,Rekha SS,Muniandy S,Salleh N

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:Flavonoids, which have been identified in a variety of plants, have been demonstrated to elicit beneficial effects on memory. Some studies have reported that flavonoids derived from Erythrina plants can provide such beneficial effects on memory. The aim of this study was to identify the flavonoids present in...

journal_title：BMC complementary and alternative medicine

authors： de Oliveira DR,Zamberlam CR,Gaiardo RB,Rêgo GM,Cerutti JM,Cavalheiro AJ,Cerutti SM

更新日期：2014-08-05 00:00:00

abstract：BACKGROUND:Flavonoid-rich aqueous fraction of methanolic extract of Hibiscus sabdariffa calyx was evaluated for its anti-hepatotoxic activities in streptozotocin-induced diabetic Wistar rats. METHODS:Diabetes Mellitus was induced in Wistar rats by a single i.p injection of 80 mg/kg b.w. streptozotocin (STZ) dissolved ...

journal_title：BMC complementary and alternative medicine

authors： Adeyemi DO,Ukwenya VO,Obuotor EM,Adewole SO

更新日期：2014-07-30 00:00:00

abstract：BACKGROUND:Bushen-Qiangdu-Zhilv Decoction (BQZ) is one of famous traditional Chinese medical formula for treating ankylosing spondylitis (AS). However, the mechanisms underlying effects of BQZ remains unknown. Pro-inflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-1, play an important role in AS...

journal_title：BMC complementary and alternative medicine

authors： Huang RY,Lin JH,He XH,Li X,Lu CL,Zhou YY,Cai J,He YT

更新日期：2014-07-28 00:00:00

abstract：BACKGROUND:Artemisia capillaris (AC) has been recognized as one of the promising candidates for hepatoprotective, hypoglycemic, hypolipidemic, antiobesitic and anti-inflammatory therapeutic effectiveness. This study evaluated the inherent mechanism and anti-apoptotic activity of 30% ethanol extract of AC (AC extract) 1...

journal_title：BMC complementary and alternative medicine

authors： Jang E,Shin MH,Kim KS,Kim Y,Na YC,Woo HJ,Kim Y,Lee JH,Jang HJ

更新日期：2014-07-19 00:00:00

abstract：BACKGROUND:Complementary and alternative medicine (CAM) is frequently used in the Middle East, especially to treat chronic diseases such as infertility. We aimed to examine the prevalence, characteristics, and determinants of CAM use, particularly herbs and antioxidant therapies, among infertile males presenting for in...

journal_title：BMC complementary and alternative medicine

authors： Bardaweel SK

更新日期：2014-07-16 00:00:00